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All website slow

ManuG2k

Basic Pleskian
Hello,
I have Plesk 11.0.9 Update #47 on Linux Ubuntu 12.04 (I used ISO images http://www.parallels.com/download/plesk/images/)

I have 123 domain configured and active.
The ngix proxy is active.

All website are often very slow.

Plesk is installed on a Virtual Machine with 4 vCPU and ram 10Gb.
CPU usage is 10% on average
RAM usage is 40% on average

If I restart the server, many website is very slow however.
When the sites are slow, there is still a lot of RAM available and a lot of cpu.

The VM was originally installed with 2 vcpu and 4 gb of ram.
You must configure plesk to optimize the use of ram and cpu (like startserver, maxclients, minsparethreads etc etc) ?

Can you help me ?
 
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