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The APS Catalog has been deprecated and removed from all Plesk Obsidian versions. Applications already installed from the APS Catalog will continue working. However, Plesk will no longer provide support for APS applications.
Please be aware: with the Plesk Obsidian 18.0.78 release, the support for the ngx_pagespeed.so module will be deprecated and removed from the sw-nginx package.
How did you attach mysql db server (on 3350 port)? The only correct way is to add it via control panel>Tools & Settings>Database servers.
As I undestand you have installed mysql besides mysql wich is provided by Parallels.
I have no issue under such workflow:
install pp
install mysql (5.6 in my case) with user which has access to any host - for remote connection
add it to Database servers
after that launching of AI does not cause removing of mysql db server and all commot task were performed correctly/