There is also an option to allow open relay without authorization, which, by default, is hidden from the user interface. Opening mail relay without authorization is not recommended because it allows spammers to send unsolicited mail through your server. If you want to set the open relay, log in to the server’s file system, locate the file root.controls.lock in your Plesk installation directory (PRODUCT_ROOT_D/var/root.controls.lock on Linux and PRODUCT_DATA_D/var/root.controls.lock on Windows platforms) and remove the line /server/mail.php3:relay_open from this file. The open relay option will appear in your control panel.
In Plesk for Windows, if you do not wish to use relay restrictions for networks that you trust, specify the network IP and mask in the Use no relay restrictions for the following networks field.