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Issue Mail queue very slow with 10 min delay

From the screenshot, I see the spamd-child was able to process 4 emails and it did it pretty fast. Do you have same screenshot of logs but for email that stuck for 10 mins?

Unfortunately, I don't have ideas about the warn: plugin: [...], maybe it is something related file permissions?..
 
I am pretty sure @AYamshanov is right. The "warn: plugin: eval failed: bayes ... cannot create tmp lockfile" is likely caused because of file/directory permissions issues. I kinda doubt that's the cause of your mail queue issue tough, but you never know. For troubleshooting purposes you could disable the bayes plugin for SpamAssassin to see if that improves your situation.

You can disable bayes by adding use_bayes 0 to /etc/mail/spamassassin/local.cf and restarting SpamAssassin afterwards (or amavisd if you're using PES).
 
new update, the queue now is working well.
It seems that the issue is caused by the function "enable the personal settings to the spam filter" (i hope it's the right translation for this) in the antispam filter settings.
For now i have disabled this function.
 
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