Please assess my server (Apache) configuration

[linuxxphybrid]

I have been having problems on my web server (Apache). I did a few things to address problems, but I'm guessing that the server is not configured right (given hardware and workload). The following is my server configuration, a copy of httpd.conf. Please assess and let me know what changes I should make. More specifically, I'd like to know if the configuration can make Apache lock up or hang; if so, I need to make changes in order not to let that happen.

Timeout 300
KeepAlive Off
MaxKeepAliveRequests 100
KeepAliveTimeout 15

<IfModule prefork.c>
StartServers 8
MinSpareServers 5
MaxSpareServers 20
MaxClients 256
MaxRequestsPerChild 4000
</IfModule>