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We can give you common recommendations which can help you to eliminate spam attack like using MAPS zones, spamassassin, blacklists, rejecting emails for non-existing users, update Plesk to the latest version and configure SPF technology, etc. The following articles are devoted to troubleshooting spam and known issues with spamassassin:
Somebody is sending SPAM from my server. This results in the main server IP getting blacklisted.
1. How to identify the spammer on my server .. or the compromised account?
Can the sender be identified from: C9EEDB720A4B4A5CA487B4AB3CD7BF3A.MAI
or
ME-I0018: [F8E9D6D22AC34047B86D7CB83E3C75FA.MAI] Outbound message from ([SMTP:[email protected]]) requeued as [300E2AA30B7F4A40974C3973FC9F47D4.MAI] to the target domain [some_domain.com]
2. How to further secure the server to prevent sending such spam messages?
Emails are sent using the 'From' field containing email IDs of Yahoo, AOL, Gmail, etc.
3. Is there any way to limit the number of messages that can be sent in an hour from a particular hosting account?