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Issue Huge load average, uninterruptible state

This issue sounds like it scales with traffic (if you always had high wait time then that might point to an underlying infrastructure issue). You can likely rule ot a Plesk-related update problem at this point so when the issue is occurring, it might help to see if the traffic loads are being caused by bots or brute force attacks by looking at the top exernal IPs accessing the system:

# netstat -nt | awk '/^tcp/ {print $5}' | awk -F: '{print $1}' | sort | uniq -c | sort -n

It would also help to take a look at the sites that are being access and look at their individual error/access logs as well.
 
You're currently using phpfpm 7.3. It works and resource usage is normal. Now you switch to 7.4, and it spikes? What is the resource usage difference between the two. X GB of ram? X amount of cpu?
what if i am using the latest php version is it really affect?
 
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