Thanks for your help. What i did is to upgrade to 12.5. Then i get this issue with Apache Module. If i hover over the exclamation mark i get in a pop up "handler can not be activated apache module is switch off". How can i switch on the apache module?
Edit: Found an entry in .htaccess from webserver. Get 500 internal server error there would be an php_value in it what no needed anymore. I switched over to fastcgi delete php_value entry in .htaccess. If someone use OTS Open Ticket System, please check htaccess entry.