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Question Roundcube doesn't work

I found: I had a DNS configuration problem, now I have access to roundcube but I can't send an email through roundcube, I have this error message: SMTP Error (250): Authentication failed

How to fix the problem?
 
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Thank you for your answer.

On this page Unable to send email from RoundCube: SMTP server does not support authentication they say:

Before:
$config['smtp_server'] = 'mail.example.com';

After:
$config['smtp_server'] = 'tls://mail.example.com';

But into my /usr/share/psa-roundcube/config/defaults.inc.php file I find: $config['smtp_server'] = 'localhost';

Should i change this variable by: $config['smtp_server'] = 'tls://localhost';

What is the right port number of config['smtp_port']: 587 or 25?

An other question, with Let's encrypt I added a ssl certificate for my domain but it does not display correctly, how to fix the problem?
 
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