Well, after banging my head against the wall for quite some time now, I figured I'd give posting here a try, and see if anyone has encountered this problem before. Before you start suggesting applying the hotfix and whatnot, know that all of that has been done. I'm well aware of the problems that the hotfix repairs, and have run it a few times on the server, just to be sure. The funny thing is, the control panel was working just fine, and suddenly, *poof* you could no longer get to the main domain adminstration page when clicking on a domain name. All it gives you is a blank page in that frame. Here's a screenshot: Does anyone have any suggestions as to what to try? The thing that really gets me the most, is that is was working fine one minute..the next, it wasn't.